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Rick

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Rick last won the day on February 19

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  1. Hi, I hope you had a good holiday and a happy new year. Just a short update this week, since as I mentioned last time, New Zealand pretty much closes down from mid-Dec to mid-Jan for the holidays. Things will finally be coming back to life next week. On the science side, the protein from the second fabrication batch that I mentioned in my last update is now in-hand. As the last step of fabrication, we run the dissolved compound through a 0.2 micron filter, which effectively sterilizes it. After that, it can be safely stored at 4C (in a standard refrigerator). The
  2. Hi, Our crowdfunding campaign is now complete. We raised NZ $24,200 (about USD $17,000). Thanks again to those who donated! We have recently completed fabrication of the second batch of our protein, with significantly improved purity and yield. Excellent progress. We are now working on replicating some of the basic antiviral functionality described in the 2011 paper about DRACO. There is a surprising amount of interesting and complex science involved. We are anticipating that several iterations of fabrication and testing may be required. In case you haven't b
  3. Hi, Our crowdfunding campaign is coming down to its last 48 hours. Thanks if you have already donated. In case you haven't had a chance to check out the campaign recently, here's a link: https://donate.kimermed.co.nz/campaign/2/ending-viral-disease Since the last Weekly Update, there have been a couple of new posts in the members only section of the forum: https://forum.kimermed.co.nz/index.php?/forum/15-general-discussion/ If you made a donation more than about a week ago and don't yet have access to that part of the forum, please let me know (more recent
  4. Rick

    Delivery method

    The molecular weight of VTose is roughly 35 kDa. One of the earliest papers about transduction tags showed effectiveness with a protein with a MW of 120 kDa: In vivo protein transduction: delivery of a biologically active protein into the mouse - PubMed (nih.gov) Transport of even larger proteins is undoubtedly possible.
  5. Specific treatment protocols is one of the things we will be researching. We certainly will also be putting some effort into trying to develop an oral form. However, proteins are very susceptible to damage and degradation by the digestive system, so it's a challenge. Insulin, for example, which is a relatively small peptide (a short protein), still doesn't have an oral form.
  6. For Rider's study with mice to treat Influenza, he only treated them for a few days. Dosing in humans will depend on a number of factors, such as the type of virus being treated, the severity of the infection, whether there are other viral co-infections, and so on. We are also looking at formulation changes that are intended to influence the required dose. The specifics in this area are one of the many things that we plan to determine during clinical trials.
  7. We've completed the first week of our crowdfunding campaign! Thanks if you have already donated. If you haven't had a chance to donate yet, here's a link: https://donate.kimermed.co.nz/campaign/2/ending-viral-disease Donations of any amount are welcome and appreciated. I've just made the first post in the new members-only section of the forum: Sample antiviral cytopathic effect test results If you aren't a member yet, you can become one by either subscribing on the forum, or by donating NZ $35 (US $23) or more on the crowdfunding site. Note that subscrip
  8. Our Crowdfunding Campaign started today! https://donate.kimermed.co.nz/campaign/2/ending-viral-disease
  9. Our crowdfunding campaign is now live! https://donate.kimermed.co.nz/campaign/2/ending-viral-disease It will run for the next 30 days. Our goal is to raise at least NZ $50,000 (USD $33,000). For donations of $100 or more, you can choose to sponsor a particular virus. The way this works is that you can pick a virus that interests or concerns you from a list, and we will direct 50% of your donation toward research on that virus. We also look at sponsorship as a kind of dollar-weighted vote, to help us prioritize our research. We are also offering discount
  10. Thanks for the suggestion. I was under the impression that USAMRIID only works with US-based companies, but I'll have another look.
  11. Hi, Just a short update this week, but with some exciting news. First, our crowdfunding campaign will begin on Sun Nov 15! More details as we get closer. In addition, we have started fabricating the first batch of our compound. It's a bit of a process, so it takes a while. This batch will be a relatively small run, but it should produce enough for us to do some testing. Thanks for your continued interest and support. Regards, --Rick Our vision is the end of all viral disease in humans, pets and livestock.
  12. Yes, exactly! We have a few other ideas along similar lines, too.
  13. Hi, We are continuing to make good progress on the upcoming crowdfunding campaign. I don't have a date to announce yet, but hope to have one for you soon. Things on the science side are coming along nicely. We have now put two labs under contract. We've also had some excellent input from our science advisers regarding our research and development plan. In fact, I'm sensing considerable excitement on that front. Now all we need now is the funding! There was some alarming news recently: https://www.eurekalert.org/pub_releases/2020-10/uonc-scr101320.php
  14. HPV can be a bit challenging to test against, so we haven't made a definitive decision regarding strain yet. At the moment, one of the labs we're talking to does a lot of work with HPV16, so we may start there. Our expectation is that effectiveness shouldn't vary much from one strain to another, but that is, of course, something we will need to test.
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